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Januvia Tablets (Sitagliptin Tablets) – Product Information
Januvia is a drug that reduces blood sugar (glucose) levels, in type 2 diabetes (non-insulin dependent diabetes). The tablet is available in strengths of 25 mg, 50 mg and 100 mg.
Name of Drug
Januvia This medication is also known as Sitagliptin Phosphate tablets.
Manufacturer Of Januvia Tablets
Merck Sharp and Dohme
Active Pharmaceutical Ingredient
The active pharmaceutical ingredient contained in Januvia is Sitagliptin Phosphate.
Januvia (Sitagliptin) is an oral anti diabetic medicine for type 2 diabetes, helping to control blood sugar levels. It also helps regulate post prandial (after meals) insulin levels in the body. Sitagliptin is sometimes used in combination with other anti-diabetic medicines also, such as Metformin.
Januvia is an anti-diabetic drug that increases the secretion of naturally produced Incretin hormones in the body.
Januvia Tablets (Sitagliptin Tablets) – Dosage
The adult dosage of Januvia is one 100 mg tablet once daily. Januvia can be taken before or after meals (monitor blood sugar regularly).
Januvia dosage in renal insufficiency varies between 25 mg to 50 mg (Please check with your physician).
Renal function should be assessed prior and periodically during treatment. Do not crush, chew, or break Sitagliptin tablets (Januvia). Swallow the whole tablet.
Drug Class and Mechanism
Januvia is an oral drug that reduces blood sugar (glucose) levels in patients with type 2 diabetes. After a meal, Incretin hormones (GIP 1 and GIP 2) are released by the intestine, and their levels increase in the blood. Incretin hormones reduce blood glucose by increasing the production, and the release of insulin from the pancreas. Incretin hormones also reduce blood glucose by reducing the secretion of Glucagon (hormone that increases the production of glucose by the liver and raises the blood glucose levels) from pancreas. The net effect of increased release of Incretin hormones is to reduce blood glucose levels. Januvia also inhibits the enzyme DPP-4, that destroys Incretin hormones, and thereby increasing the level and activity of Incretin hormones. As a result, blood glucose levels fall. To summarize, Januvia reduces blood glucose levels by inhibiting DPP-4 and increasing the levels of Incretin hormones.
Missed Dosage Instructions for Januvia Tablets
If you miss a Januvia dose, take one as soon as you can. But if the next scheduled dose time is near, wait until that next dose timing, and just skip the one you've already missed.
Caution: You should NEVER take double doses or extra tablets of Januvia. Consult your physician further about missed doses, for any other special instructions.
Storage Instructions for Januvia Tablets
Store Januvia tablets at a cool place (25-30 degree Celsius temperature). Keep tablets away from direct sunlight and moisture.
Warnings and Precautions to be taken when using Januvia Tablets
Before using Januvia Tablets (Sitagliptin Tablets) please inform your doctor about all the medicines that you take including no prescription medications, over the counter medicines and herbal remedies. A few instances of fatal and non-fatal pancreatitis have been reported following use of Januvia. Acute kidney failure and severe hypersensitivity reactions have been reported in a few cases.
In pregnancy Januvia should be only taken, if clearly needed. (Please consult a physician before use). Nursing mothers should not use Januvia, as it is excreted in breast milk.
Keep away from children.
Side Effects of Januvia Tablets
Januvia is usually well tolerated. But in a few cases it is recommended to get medical help, if any of the following possible side effects occur after Januvia tablet intake.
Upper respiratory infection
Stuffy nose, runny nose or sore throat
Stomach Upset and Diarrhoea
Swelling of the hands or legs
Elevated liver enzymes
Tell your doctor if you have any side effect that bothers you, is unusual or does not go away.
Januvia – Drug Interactions
Januvia may mildly increase the concentration of Digoxin (Lanoxin) in the body when both drugs are being taken, thus Digoxin concentrations should be monitored appropriately. Januvia’s use with sulfonylureas and insulin reduces the blood sugar level.
Buy Januvia 100 mg Tablets (Sitagliptin Tablets) Online
You can buy Januvia Tablets online at a Cheap rate from the Swiss Pharmacy. Sitagliptin is available in pills of 25 mg, 50 mg & 100 mg . The 100 mg pills are priced at only $3.21 per unit if you place an order for 140 tablets.
This Product was added to our catalogue on Wednesday, 28. November 2012.