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Indivan Capsules – Product Information
Indivan is used in the treatment of human immunodeficiency virus (HIV) infection. Indivan (Indinavir Sulfate) is an inhibitor of the human immunodeficiency virus (HIV) protease. Each capsule of Indivan contains Indinavir sulphate equivalent to Indinavir 400 mg.
Name of Drug
Manufacturer Of Indivan Capsules
Active Pharmaceutical Ingredient
The active pharmaceutical ingredient contained in Indivan capsules is Indinavir Sulfate.
Uses Of Indivan Capsules
Indivan Capsules is used to treat HIV infection in some patients, when used in combination with certain other medicines called antiretroviral agents.
Indivan is an HIV protease inhibitor. It works by slowing the growth of HIV, the virus that causes AIDS.
Indivan Capsules – Dosage
Use Indivan as directed by your doctor. Check the label on the medicine for exact dosing instructions. The recommended dosage of indinavir is 800 mg (usually two 400-mg capsules) orally every 8 hours.
- An extra patient leaflet is available with Indivan. Talk to your pharmacist if you have questions about this information.
- For optimal absorption, indinavir should be administered without food but with water 1 hour before or 2 hours after after eating. You may also take it with a light meal that is low in calories, fat, and protein e.g., dry toast with jelly, juice, and coffee with skim milk and sugar. Take Indivan with water. You may also take it with other liquids such as skim milk, juice, coffee, or tea.
- Drinking extra fluids while you are taking Indivan is recommended. You should drink at least 48 ounces (1.5 L) of water a day unless otherwise directed by your doctor.
- If you take didanosine, ask your doctor or pharmacist how to take it with Indivan.
- Large amounts of garlic may decrease the effectiveness of Indivan. Talk with your doctor before including garlic in your diet.
- Eating grapefruit or drinking grapefruit juice while you are taking Indivan may increase the amount of Indivan in your blood, which may increase your risk for serious side effects. Talk with your doctor before including grapefruit or grapefruit juice in your diet.
- Take Indivan on a regular schedule every 8 hours around the clock, unless otherwise directed by your doctor.
- Take Indivan regularly to receive the most benefit from it. Taking Indivan at the same time each day will help you remember to take it.
- Continue to take Indivan even if you feel well. Do not miss any doses.
- If you miss a dose of Indivan by more than 2 hours, do not take that dose. Take your next dose as scheduled. If you miss the dose by less than 2 hours, take that dose immediately and then return to your regular dosing schedule. It is important not to miss doses of Indivan. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Indivan .
Drug Class and Mechanism
HIV causes the immune system to break down so that it can no longer fight off other infections. This leads to the fatal disease known as acquired immune deficiency syndrome (AIDS).
HIV thrives by taking over the immune system's vital CD4 cells (white blood cells) and using their inner workings to make additional copies of itself. Indivan belongs to a class of HIV drugs called protease inhibitors, which work by interfering with an important step in the virus's reproductive cycle. Although Indivan cannot eliminate HIV already present in the body, it can reduce the amount of virus available to infect other cells.
Indivan Capsules - Storage
Store Indivan capsules at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in the original bottle. Store away from heat, moisture, and light. Do not store in the bathroom. Leave the desiccant in the bottle. Do not eat the desiccant. Keep Indivan out of the reach of children and away from pets.
Warnings and Precautions to be taken when using Indivan capsules
Do NOT use Indivan if:
- you are allergic to any ingredient in Indivan
- you are taking alfuzosin, amiodarone, astemizole, atazanavir, certain benzodiazepines (eg, alprazolam, midazolam, triazolam), certain HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin), cisapride, an ergot derivative (eg, ergonovine, ergotamine), erythromycin, pimozide, a proton pump inhibitor (eg, omeprazole), rifampin, a serotonin 5-HT1 receptor antagonist (eg, eletriptan, sumatriptan), St. John's wort, or terfenadine
Contact your doctor or health care provider right away if any of these apply to you.
Before using Indivan:
Some medical conditions may interact with Indivan. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have cirrhosis, liver or kidney problems, diabetes, high blood sugar, high cholesterol, kidney stones, urinary problems (eg, white blood cells in the urine), or blood problems (eg, hemophilia hemolytic anemia)
Some MEDICINES MAY INTERACT with Indivan. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Amiodarone, astemizole, certain benzodiazepines (eg, alprazolam, midazolam,triazolam), cisapride, ergot alkaloids (eg, ergotamine), erythromycin, pimozide, and terfenadine because serious side effects such as increased or prolonged sedation or breathing problems, seizures, blood vessel problems, or heart problems (eg, irregular heartbeat) may occur
- Atazanavir because it may increase the risk of a buildup of bilirubin in the blood
- Proton pump inhibitors (eg, omeprazole), rifampin, or St. John's wort because they may decrease Indivan 's effectiveness
- Alfuzosin, certain HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin), conivaptan, ranolazine, serotonin 5-HT1 antagonists (eg, eletriptan, sumatriptan) because the risk of their side effects may be increased by Indivan
- Many prescription and nonprescription medicines (eg, used for infections, inflammation, aches and pains, high blood pressure, high cholesterol, heart problems, anxiety, mood or mental problems, depression, sinus problems, erectile dysfunction, seizures, other medicines used for HIV infection), multivitamin products, and herbal or dietary supplements (eg, herbal teas, coenzyme Q10, garlic, ginseng, ginkgo) may interact with Indivan , increasing the risk of side effects
This may not be a complete list of all interactions that may occur. Ask your health care provider if Indivan may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Important safety information:
- Indivan may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Indivan with caution. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to it.
- Indivan is not a cure for HIV infection. Patients may still get illnesses and infections associated with HIV. Remain under the care of your doctor.
- Indivan does not stop the spread of HIV to others through blood or sexual contact. Use barrier forms of contraception (eg, condoms) if you have HIV infection. Do not share needles, injection supplies, or items like toothbrushes or razors.
- When your medicine supply is low, get more from your doctor or pharmacist as soon as you can. Do not stop taking Indivan , even for a short period of time. If you do, the virus may grow resistent to the medicine and become harder to treat.
- Indivan may improve immune system function. This may reveal hidden infections in some patients. Tell your doctor right away if you notice signs or symptoms of an infection (eg, fever, sore throat, weakness, cough, shortness of breath) after you start Indivan
- Changes in body fat may occur while you are taking Indivan (eg, increased fat in the upper back and stomach areas, decreased fat in the arms and legs). The cause and long-term effects of these changes are unknown. Discuss any new questions or concerns with your doctor.
- Indivan may raise your blood sugar. High blood sugar can make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor immediately.
- Diabetes patients - Indivan may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Hormonal birth control (eg, birth control capsules) may not work as well while you are using Indivan . To prevent pregnancy, use an extra form of birth control (eg, condoms).
- Lab tests, including liver function tests, cholesterol tests, blood counts, and CD4 counts, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
- Caution is advised when using Indivan in CHILDREN; they may be more sensitive to its effects, especially kidney stones.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. Mothers infected with HIV should not breast-feed. There is a risk of passing the HIV infection or Indivan to the baby. It is not known if Indivan is found in breast milk. Do not breast-feed while taking Indivan.
Side Effects of Indivan capsules
Below are listed the possible side effects of Indivan Capsules. it should be noted that many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
- Bad taste in the mouth; diarrhea; dizziness; drowsiness; headache; nausea; tiredness; vomiting; weakness.
Seek medical attention right away if any of these SEVERE side effects occur:
- Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue);
- back, flank, or side pain;
- bloody or cloudy urine;
- change in the amount of urine; changes in appetite;
- chest pain; chills; confusion; dark urine;
- fast or irregular heartbeat;
- fever; flushed face; heartburn; ingrown toenails;
- joint or muscle aches; mental or mood changes;
- numbness of the mouth; one-sided numbness or weakness;
- pain while urinating; pale stools;
- red, swollen, or blistered skin;
- severe dizziness or fainting;
- severe or persistent stomach pain or upset;
- speech problems;
- swelling of the feet, hands, lower legs, or stomach;
- unusual hair loss; unusual paleness; unusual tiredness; unusually dry skin; vision changes; weight changes; yellowing of the skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects.
Buy Indivan Capsules 400 mg mg Online
You can buy Indivan Capsules online from the Swiss Pharmacy. They are available in pills of 400 mg. Indivan Capsules are priced at only $1.86 per unit if you place an order for 180 tablets.
This Product was added to our catalogue on Monday, 31. January 2011.