Paroxetine Tablets (Pexep) – Product Information
Paroxetine (Pexep Tablets or Paroxetine Hydrochloride) is an anti-depressant drug used for treating depression or obsessive-compulsive disorder (OCD).
We also stock Olanzapine tablets (Oleanz 2.5 mg, 5 mg, 7.5 mg & 10 mg tablets) which are used in the treatment of Bipolar Disorder, Depression and Schizophrenia.
Name of Drug
Paroxetine Tablets: We supply Pexep by Intas Pharmaceuticals Ltd. Website intaspharma.com
Paroxetine Tablets are also known as Pari and Parotin.
Active Pharmaceutical Ingredient in Pexep Tablets
The active pharmaceutical ingredient contained in Paroxetine Pills (Pexep Tablets) is Paroxetine Hydrochloride.
Uses of Pexep Tablets (Paroxetine HCl)
Pexep (Paroxetine HCl) Tablets is used for treating depression or obsessive-compulsive disorder (OCD). It may be used to treat panic disorder or posttraumatic stress disorder (PTSD). It may also be used to treat generalized anxiety disorder or social anxiety disorder. It may also be used for other conditions as determined by your doctor.
Paroxetine Tablets – Dosage
Use Paroxetine (Pexep Tablets) as directed by your doctor. The recommended dose per day is 20-60 mg once a day in the morning with or without food.
Take Paroxetine tablets by mouth with or without food.
Swallow Paroxetine whole. Do not break, crush, or chew before swallowing.
Taking Pexep Tablets at the same time each day will help you remember to take it.
Continue to take Paroxetine even if you feel well. Do not miss any doses. Do not suddenly stop taking Paroxetine HCl tablets without checking with your doctor. Side effects may occur. They may include mental or mood changes, numbness or tingling of the skin, dizziness, confusion, headache, trouble sleeping, or unusual tiredness. You will be closely monitored when you start Paroxetine and whenever a change in dose is made.
Drug Class and Mechanism
Paroxetine Hydrochloride is a selective serotonin reuptake inhibitor (SSRI). It works by restoring the balance of serotonin, a natural substance in the brain, which helps to improve certain mood problems.
Missed Dose
If you miss a dose of Pexep tablets (Paroxetine), take it as soon as you can. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take double or extra doses.
Storage Instructions for Pexep tablets (Paroxetine HCl Pills)
Store Pexep tablets (Paroxetine HCl) at controlled room temperature between 20-25 degrees C (68-77 degrees F).
Warnings and Precautions to be taken when using Paroxetine Pills (Pexep Tablets)
Do NOT use Paroxetine Tablets if:
- you are allergic to Paroxetine HCl or any inactive ingredient in Paroxetine Tablets
- you are taking or have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), selegiline, or St. John’s wort within the last 14 days
- you are taking a fenfluramine derivative (eg, dexfenfluramine), nefazodone, pimozide, a serotonin norepinephrine reuptake inhibitor (SNRI) (eg, venlafaxine), sibutramine, thioridazine, or tryptophan
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Paroxetine HCl (Pexep Tablets). Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you or a family member has a history of bipolar disorder (manic-depression), other mental or mood problems, suicidal thoughts or attempts, or alcohol or substance abuse
- if you have a history of seizures, heart problems, liver problems, severe kidney problems, stomach or bowel bleeding, narrow-angle glaucoma, diabetes, or metabolism problems
- if you are dehydrated, have low blood sodium levels, or drink alcohol
- if you will be having electroconvulsive therapy (ECT)
Some MEDICINES MAY INTERACT with Paroxetine HCl (Pexep Tablets)
Before using Paroxetine (Pexep Tablets) tell your health care provider all the medicines that you take including no prescription medications, over the counter medicines and herbal remedies. It is very important to inform your doctor if you are taking any other medicines, especially any of the following:
- Anorexiants (eg, phentermine), cimetidine, fenfluramine derivatives (eg, dexfenfluramine), linezolid, lithium, MAOIs (eg, phenelzine), metoclopramide, nefazodone, selegiline, serotonin 5-HT1 receptor agonists (eg, sumatriptan), sibutramine, SNRIs (eg, venlafaxine), St. John’s wort, tramadol, trazodone, or tryptophan because severe side effects, such as a reaction that may include fever, rigid muscles, blood pressure changes, mental changes, confusion, irritability, agitation, delirium, and coma, may occur
- Anticoagulants (eg, warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) because the risk of bleeding, including stomach bleeding, may be increased
- Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood sodium levels may be increased
- Antiarrhythmics (eg, flecainide, propafenone, quinidine), H1 antagonists (eg, astemizole, terfenadine), or phenothiazines (eg, chlorpromazine, thioridazine) because severe heart problems, including irregular heartbeat, may occur
- Cyproheptadine, HIV protease inhibitors (eg, ritonavir), phenobarbital, or phenytoin because they may decrease Paroxetine ‘s effectiveness
- Aripiprazole, atomoxetine, clozapine, fluoxetine, pimozide, procyclidine, risperidone, theophylline, or tricyclic antidepressants (eg, amitriptyline) because the risk of their side effects may be increased by Paroxetine
- Digoxin or tamoxifen because their effectiveness may be decreased by Paroxetine
Side Effects of Paroxetine Tablets
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects of Pexep Tablets persist or become bothersome:
- Anxiety; blurred vision; constipation; decreased sexual desire or ability; diarrhea; dizziness; drowsiness; dry mouth; gas; increased sweating; increased urination; loss of appetite; nausea; nervousness; stomach upset; trouble concentrating; trouble sleeping; unusual skin sensations; weakness; yawning.
Seek medical attention right away if any of these SEVERE side effects occur:
- Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bizarre behavior; black or bloody stools; chest pain; exaggerated reflexes; fast or irregular heartbeat; fever, chills, or sore throat; hallucinations; loss of coordination; new or worsening agitation, panic attacks, aggressiveness, impulsiveness, irritability, hostility, exaggerated feeling of well-being, restlessness, or inability to sit still; persistent or severe ringing in the ears; persistent, painful erection; red, swollen, blistered, or peeling skin; seizures; severe or persistent anxiety or trouble sleeping; significant weight loss; stomach pain; suicidal thoughts or attempts; tremor; unusual bruising or bleeding; unusual or severe mental or mood changes; vision changes; worsening of depression.
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