Anazole Tablets (Anastrozole 1 mg) – Product Information
Anazole (Anastrozole tablets) is used for the treatment of early breast cancer in hormone receptor positive post-menopausal women. It is also used in the adjuvant treatment of early breast cancer in hormone receptor positive postmenopausal women who have received 2 to 3 years of adjuvant Tamoxifen. It is also used for reduction in the incidence of contralateral breast cancers in post menopausal women receiving as adjuvant treatment for early breast cancer and treatment of advanced breast cancer in post-menopausal women.
Anazole tablets are used offlabel by male bodybuilders as part of their Post Cycle Therapy (PCT) to restore the natural level of testosterone in the body, so that they can avoid the undesirable effects of estrogen such as gynecomastia that can occur at the end of a steroid cycle.
Anazole tablets are manufactured by Alpha-Pharma Healthcare, India in the strengths of 1 mg of Anastrozole.
Compared to Tamoxifen, it is more effective and has fewer side effects. Anastrozole tablets are available in strength of 1 mg.
Anastrozole has also been tested for reducing estrogens, including estradiol, in men.
We also have in stock Letrozole tablets(Letromina 2.5 mg tablets) and Nolvadex tablets which are medications that are used to treat the same indication.
Name of Drug
Anazole 1mg tablets. Anazole tablets are also known as Generic Anastrozole 1 mg tablets
Manufacturer of Anazole Tablets
Alpha-Pharma Healthcare
Website:www.alpha-pharma.com
Active Pharmaceutical Ingredient
The active pharmaceutical ingredient contained in Anazole tablets is Anastrozole. Each Anazole tablet contains 1 mg of Anastrozole.
Uses of Anastrozole Tablets
Anastrozole tablets is used to treat breast cancer in women after the change of life (menopause). Anazole does not kill cancer cells, but it stops or slows their growth. Anastrozole is a non-steroidal aromatase inhibitor, which reduces the amount of oestrogen (female sex hormone) made by the body. In certain types of breast cancer, oestrogen can help the cancer cells grow. By blocking oestrogen, Anazole may slow or stop the growth of the cancer.
Anastrozole Tablets (Anazole) – Dosage
The recommended adult dosage of Anastrozole tablets is one 1 mg tablet taken once daily. You can take Anazole before or after food.
Drug Class and Mechanism
Generic Anastrozole 1 mg (Anazole) is a potent and highly selective nonsteroidal aromatase inhibitor. Anastrozole 1 mg selectively inhibits the conversion of androgens to estrogens, without affecting synthesis of adrenal corticosteroid, aldosterone or thyroid hormone.
In post-menopausal women, ovarian secretion of estrogen declines, and conversion of adrenal androgens into estrone and estradiol in peripheral tissues, catalysed by the aromatase enzyme (estrogen synthase) is the principal source of estrogens. Many breast cancers also contain aromatase and the importance of tumour-generated oestrogens is uncertain.
Reducing circulating oestradiol levels has been shown to produce a beneficial effect in women with breast cancer. In postmenopausal women, Anazole at a daily dose of 1 mg produced oestradiol suppression of greater than 80% using a highly sensitive assay.
What to do in Case You Miss a Dose of Anastrozole
In case you miss a dose of Anastrozole 1 mg tablets, take the missed dose as soon as you remember it. In case, it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed dose.
Storage Instructions for Anastrozole Tablets
Keep Anastrozole tablets in a cool, dry place at controlled room temperature. Store below 30°C. Protect from heat and moisture. Keep Anastrozole tablets in a safe place where children cannot see or reach them.
Warnings and Precautions to be taken when using Anazole Tablets
Before using Anastrozole Tablets please inform your doctor all the medicines that you take including no prescription medications, over the counter medicines and herbal remedies. The other precautions to be taken when using Anazole (Anastrozole 1 mg tablets) are:
- Anastrozole tablets (Anazole 1 mg) is not recommended for use in children or in pre-menopausal women as safety and efficacy have not been established in these groups of patients.
- In women with pre-existing ischemic heart disease, an increased incidence of ischemic cardiovascular events occurred with use of Anazole 1 mg tablets compared to Tamoxifen use. Consider risks and benefits.
- Anazole is contraindicated in women who are pregnant, think you may be pregnant, or plan to get pregnant.
- Decreases in bone mineral density can occur. Consider bone mineral density monitoring.
- Increases in total cholesterol may occur. Consider cholesterol monitoring.
- An increases in total amount of cholesterol may occur. Cholesterol monitoring is recommended.
- Simultaneous use of Tamoxifen and/or other treatment with medications containing estrogens should not be used with Anastrozole, as it’s pharmacological actions may be reduced.
Side Effects of Anastrozole Tablets
The common possible side effects of Anastrozole tablets (Anazole 1 mg) which are mainly mild or moderate in nature and occurring with an incidence of 10% or more are given below: hot flashes, asthenia, arthritis, pain, arthralgia, pharyngitis, hypertension, depression, nausea and vomiting, rash, osteoporosis, fractures, back pain, insomnia, headache, peripheral edema and lymphedema, regardless of causality.
Anastrozole Tablets – Contraindications
Anastrozole is contraindicated in the following cases:
- Patients with known hypersensitivity to anastrozole or any of the inactive ingredients included in the tablets.
- Women of premenopausal endocrine status, including pregnant or lactating women.
Anastrozole During Pregnancy
Anastrozole has been classified by the US FDA as X.
Anastrozole (Anazole Tablets) may cause fetal harm when administered to a pregnant woman and offers no clinical benefit to premenopausal women with breast cancer. Generic Arimidex (Anazole Tablets) is contraindicated in women who are or can become pregnant.
In case a woman becomes pregnant, they should stop taking Anazole and immediately contact her doctor. If Anazole tablets are used during pregnancy, or in case the patient becomes pregnant while receiving this medicine, the patient should be apprised of the potential hazard to the fetus and potential risk for pregnancy loss.
Buy Anazole Tablets Online
You can buy Anazole tablets online at a cheap rate from the Swiss Pharmacy. Generic Anastrozole (Anazole) is available in pills of 1 mg . The 1 mg tablets cost only $0.78 per unit when you place an order for 720 tablets.
