Levetiracetam Tablets

Levera (Generic Levetiracetam Tablets) is used alone or together with other medicines to help control certain types of seizures in the treatment of epilepsy.

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Generic Levetiracetam Tablets (Levera Tablets) – Product Information

Generic Levetiracetam Tablets (Levera) is used alone or together with other medicines to help control certain types of seizures (eg, partial seizures, myoclonic seizures, or tonic-clonic seizures) in the treatment of epilepsy.
Levera tablets are used for the treatment of partial-onset seizures in patients 1 month of age and older. Levera is used for adjunctive therapy for the treatment of myoclonic seizures in patients 12 years of age and older with juvenile myoclonic epilepsy and primary generalized tonic-clonic seizures in patients 6 years of age and older with idiopathic generalized epilepsy.

We also stock Oleanz (Generic Olanzapine Tablets) which is used in the treatment of Bipolar Disorder, Depression and Schizophrenia.

Name of Drug

Levetiracetam   We supply Levera tablets.

Manufacturer of Levera Tablets (Generic Levetiracetam Tablets)

Intas Pharmaceuticals Ltd.
Website:www.intaspharma.com

Active Pharmaceutical Ingredient

The active pharmaceutical ingredients contained in Levera tablets is Levetiracetam. Each film-coated tablet contains 250 mg, 500 mg, 750 mg or 1000 mg of Levetiracetam.

Mechanism of Action

The precise mechanism(s) by which Levetiracetam exerts its antiepileptic effect is not known. The antiepileptic activity of Levetiracetam was studied in a number of animal models of epileptic seizures.
Levetiracetam did not inhibit single seizures induced by maximal stimulation with electrical current or different chemoconvulsants and showed only minimal activity in submaximal stimulation and in threshold tests.
Protection was observed, however, against secondarily generalized activity from focal seizures induced by pilocarpine and kainic acid, two chemoconvulsants that induce seizures that mimic some features of human complex partial seizures with secondary generalization.

Uses of Generic Levetiracetam Tablets

Levera tablets (Generic Levetiracetam tablets) is an anticonvulsant and is used with other medications to treat seizures (epilepsy).
Levera is indicated as monotherapy in the treatment of partial onset seizures with or without secondary generalisation in adults and adolescents from 16 years of age with newly diagnosed epilepsy.
Levera is indicated as adjunctive therapy in the treatment of the following:

  • in the treatment of partial onset seizures with or without secondary generalisation in adults, adolescents, children and infants from 1 month of age with epilepsy.
  • in the treatment of myoclonic seizures in adults and adolescents from 12 years of age with Juvenile Myoclonic Epilepsy.
  • in the treatment of primary generalised tonic-clonic seizures in adults and adolescents from 12 years of age with Idiopathic Generalised Epilepsy.

Levera Tablets (Generic Levetiracetam Tablets) – Dosage

The dosage for all indications for adults (18 years and greater) and adolescents (12 to 17 years) weighing 50 kg or more is given below:
The initial therapeutic dose is 500 mg twice daily. This dose can be started on the first day of treatment. However, a lower initial dose of 250 mg twice daily may be given based on physician assessment of seizure reduction versus potential side effects. This can be increased to 500 mg twice daily after two weeks.
Depending upon the clinical response and tolerability, the daily dose can be increased up to 1,500 mg twice daily. Dose changes can be made in 250 mg or 500 mg twice daily increases or decreases every two to four weeks.

Discontinuation: If Levetiracetam has to be discontinued it is recommended to withdraw it gradually (e.g. in adults and adolescents weighing more than 50 kg: 500 mg decreases twice daily every two to four weeks).

Missed Dosage Instructions for Levera Tablets

If you miss a dose of Levera, take it as soon as you remember. If it is almost time for your next dose, just skip the missed dose. Take the next dose at your regular time. Do not take two doses of your medicine at the same time.

Levera Tablets Contraindications

Levera tablets are contraindicated in persons with a hypersensitivity (allergy) to Levetiracetam or any of the other ingredients of this medicine.

Storage Instructions for Levera Tablets

Store Levera tablets in a cool dry place where the temperature stays at 25°C. (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F) Do not store it or any other medicine in the bathroom or near a sink. Keep away from children or pets.

Warnings and Precautions to be taken when using Levera Tablets (Generic Levetiracetam Tablets)

Before using tablets please inform your doctor about all the medicines that you take including no prescription medications, over the counter medicines and herbal remedies.
Behavioral abnormalities including psychotic symptoms, suicidal ideation, irritability, and aggressive behavior have been observed; monitor patients for psychiatric signs and symptoms.
Suicidal Behavior and Ideation: Monitor patients for new or worsening depression, suicidal thoughts/behavior, and/or unusual changes in mood or behavior.
Monitor for somnolence and fatigue and advise patients not to drive or operate machinery until they have gained sufficient experience on Levera
Withdrawal Seizures: Levera must be gradually withdrawn

Side Effects of Levetiracetam Tablets (Levera Tablets)

Most common Levetiracetam tablets (Levera tablets) Side Effects with an incidence rate 5% or greater and more than placebo include:
Adult patients: somnolence, asthenia, infection and dizziness
Pediatric patients: fatigue, aggression, nasal congestion, decreased appetite, and irritability
The other possible Side Effects of Levetiracetam tablets observed in in Pooled Placebo-Controlled, Add-On Studies in Adults Experiencing Partial Onset Seizures are Asthenia, Somnolence, Headache, Infection, Dizziness, Pain, Pharyngitis, Depression, Nervousness, Rhinitis, Anorexia, Ataxia, Vertigo, Amnesia, Anxiety, Cough Increased, Diplopia, Emotional Lability, Hostility, Paresthesia, Sinusitis.

Levera Tablets (Generic Levetiracetam Tablets) – Drug Interactions

The drug Interactions of are given below:
There may be an interaction between Levetiracetam (Levera Tablets) and any of the following: alcohol. antihistamines (e.g., Cetirizine, Doxylamine, Diphenhydramine, Hydroxyzine, Loratadine) antipsychotics (e.g., Chlorpromazine, Clozapine, Haloperidol, Olanzapine, Quetiapine, Risperidone)

Levera Tablets (Generic Levetiracetam Tablets) Overdosage

Other than drowsiness, there were no adverse reactions in the few known cases of overdose in clinical trials. Cases of somnolence, agitation, aggression, depressed level of consciousness, respiratory depression and coma were observed with Levetiracetam (Levera tablets) overdoses in postmarketing use.
There is no specific antidote for overdose with Levetiracetam tablets.
If indicated, elimination of unabsorbed drug should be attempted by emesis or gastric lavage; usual precautions should be observed to maintain airway. General supportive care of the patient is indicated including monitoring of vital signs and observation of the patient’s clinical status.
Standard hemodialysis procedures result in significant clearance of levetiracetam (approximately 50% in 4 hours) and should be considered in cases of overdose. Although hemodialysis has not been performed in the few known cases of overdose, it may be indicated by the patient’s clinical state or in patients with significant renal impairment.

Levera Tablets During Pregnancy

Levetiracetam (Levera tablets) is classified by the US FDA as Pregnancy Category C.
There are no adequate and well-controlled studies in pregnant women. In animal studies, Levetiracetam produced evidence of developmental toxicity, including teratogenic effects, at doses similar to or greater than human therapeutic doses. Levetiracetam extended-release tablets should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
It is not known whether is excreted in human milk.

Buy Generic Levetiracetam Tablets Online at only $0.45

You can buy Generic Levetiracetam tablets online at a cheap price from the Swiss Pharmacy.     Levera 250 mg pills are priced at only $ 0.45 per unit if you place an order for 240 tablets.

Strength

250mg, 500mg, 750mg, 1000mg

Pack Size

30 pills, 60 pills, 120 pills, 240 pills

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