Clopivas Tablets – Product Information
Clopivas (Clopidogrel Bisulphate) manufactured by Cipla is used to treat patients with non-ST-segment elevation ACS (unstable angina (UA)/non-ST-elevation myocardial infarction (NSTEMI)) and patients with ST-elevation myocardial infarction (STEMI Acute Coronary Syndrome). It is also used for treatment of patients with Recent Myocardial Infarction, Recent Stroke or Established Peripheral Arterial Disease. In short, Clopivas prevent strokes and heart attacks.
We also stock Amlopres (Generic Amlodipine Besilate tablets) which is used to treat hypertension (high blood pressure) and to treat angina (chest pain).
Name of Drug
Clopivas: We supply Clopivas manufactured by Cipla Ltd. Clopivas (Clopidogrel Bisulphate)
Manufacturer of Clopivas Tablets
Cipla Ltd.
Website: cipla.com
Active Pharmaceutical Ingredient
The active pharmaceutical ingredient contained in Clopivas Tablets is Clopidogrel Bisulphate.
Uses Of Clopivas Tablets
Clopivas is used to prevent strokes and heart attacks in persons who are at high risk. Clopivas (Clopidogrel Bisulphate) has been shown to decrease the rate of a combined endpoint of cardiovascular death, myocardial infarction (MI), or stroke as well as the rate of a combined endpoint of cardiovascular death, MI, stroke, or refractory ischemia.
Clopivas Tablets – Dosage
Take Clopivas tablets exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass of water. Clopivas (Clopidogrel Bisulphate)can be taken with or without food.
Acute Coronary Syndrome
- For patients with non-ST-elevation ACS (UA/NSTEMI), initiate clopidogrel with a single 300 mg oral loading dose and then continue at 75 mg once daily. Initiate aspirin (75–325 mg once daily) and continue in combination with clopidogrel.
- For patients with STEMI, the recommended dose of Clopivas (Clopidogrel) is 75 mg once daily orally, administered in combination with aspirin (75–325 mg once daily), with or without thrombolytics. Clopidogrel may be initiated with or without a loading dose
Recent MI, recent stroke or established PAD
- The recommended dose is 75 mg of Clopivas once daily orally, with or without food.
Drug Class and Mechanism
Clopivas is an anti-platelet drug, that is, a drug that inhibits the ability of platelets to clump together as part of a blood clot. It is similar to ticlopidine (Ticlid) in chemical structure and in the way it works. Unlike ticlopidine, Clopivas does not cause serious reductions of white cells in the blood and, therefore, routine blood testing to determine if the white blood cell count is low is not necessary during treatment. The risk of heart attacks and strokes (which usually are caused by blood clots) is increased in patients with a recent history of stroke or heart attack and patients with peripheral vascular disease. (Peripheral vascular disease is the same as atherosclerotic arterial disease or "hardening" of the arteries in which the arteries become narrowed. It frequently occurs in the legs and often causes claudication or pain in the legs upon walking). Clopivas is used to reduce the risk of heart attacks and strokes in these patients. Clopidogrel Bisulphate was approved by the FDA in 1997.
Missed Dose
Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.
Storage Instructions for Clopivas Tablets
Clopivas Tablets (Clopidogrel Bisulphate) should be stored at room temperature, 15-30 degrees C (59-86 degrees F), away from moisture and heat.
Clopivas Tablets (Clopidogrel Bisulphate) – Contraindications
- Hypersensitivity to Clopidogrel Bisulphate or any other component of the product
- Active pathological bleeding such as peptic ulcer or intracranial hemorrhage
Warnings and Precautions to be taken when using Clopivas Tablets
Tell your doctor and dentist that you are taking Clopivas (Clopidogrel Bisulphate) before having any surgical procedures. Do not take aspirin, ibuprofen (Motrin, Advil, Nuprin, others), naproxen (Aleve, Anaprox, Naprosyn, others), ketoprofen (Orudis, Orudis KT, Oruvail), indomethacin (Indocin), nabumetone (Relafen), oxaprozin (Daypro), or other non-steroidal anti-inflammatory medications (NSAIDs) without first talking to your doctor. It may take longer than usual for you to stop bleeding, even from minor wounds. Tell your doctor about any unusual bleeding or bruising that you experience. Studies in rats have shown that Clopivas appears in breast milk. However, it is not known whether it also appears in human breast milk. Because of a potential for side effects in the nursing infant, the physician must weigh the potential benefits and possible risks before prescribing Clopivas in nursing mothers.
Side Effects of Clopivas Tablets
The tolerability of clopidogrel (Clopivas Tablets)is similar to that of Aspirin. Bleeding, including life-threatening and fatal bleeding, is the most commonly reported adverse reaction. Diarrhea, rash, or itching occurs in approximately 1 in 20 persons taking clopidogrel. Abdominal pain also occurs in about 1 in 20 persons, but it is less frequent than with aspirin.
Ticlopidine (Ticlid) is an antiplatelet medication quite similar to clopidogrel. It has been associated with a severe reduction in white blood cell count in between 0.8% and 1% of persons. The risk of this dangerous side effect with clopidogrel is about 0.04%, much less than with ticlopidine but twice that of aspirin.
Clopidogrel rarely causes a condition called thrombotic thrombocytopenic purpura (TTP) in one out of every 250,000 people. TTP is a serious condition in which blood clots form throughout the body. Blood platelets, which participate in clotting, are consumed, and the result can be bleeding because enough platelets are no longer left to allow blood to clot normally. For comparison, the related drug, ticlodipine (Ticlid), causes TTP 17-50 times more frequently than clopidogrel.
More Information about Clopivas Tablets
If you experience any of the following serious side effects, stop taking Clopivas Tablets (clopidogrel) and seek emergency medical attention or notify your doctor immediately:
- an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
- bloody (or black) vomit or stools;
- severe headache, confusion, or dizziness;
- unexplained bruising or bleeding; or
- bleeding nose.
Other, less serious side effects may be more likely to occur. Continue to take Clopivas Tablets {clopidogrel} and talk to your doctor if you experience any of the following:
- upset stomach;
- diarrhea or constipation; or
- headache or dizziness.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Buy Cipla Clopivas Tablets 75 mg Online
You can buy Clopivas Tablets manufactured by Cipla online from the Swiss Pharmacy. It is available in pills of 75 mg. The 75 mg pills are priced at only $0.40 per unit if you place an order for 360 tablets.