Generic Exemestane Tablets
Generic Exemestane Tablets (Aromex Tablets) – Product Information
Generic Exemestane tablets (Aromex Tablets) is used for the adjuvant treatment of postmenopausal women with estrogen-receptor positive early breast cancer who have received two to three years of Tamoxifen and are switched to Generic Exemestane for completion of a total of five consecutive years of adjuvant hormonal therapy.
It is also used for treatment of advanced breast cancer in postmenopausal women whose disease has progressed following Tamoxifen therapy.
Generic Exemestane tablets (Aromex tablets) are also used offlabel in bodybuilding due to the fact that Exemestane acts an estrogen-inhibitor. Professional bodybuilders use Generic Exemestane tablets towards the end of a steroid cycle to restore the blood levels of testosterone in the body.
Name of Drug
Aromex tablets. They are also known as Generic Exemestane.
Manufacturer of Aromex Tablets
Active Pharmaceutical Ingredient
The active pharmaceutical ingredient present in Aromex tablets is Exemestane. Each Aromex tablet contains 25 mg of Exemestane.
Aromex Tablets - Contraindications
Aromex Tablets are contraindicated in patients with a hypersensitivity to Exemestane or any other ingredient present in Aromex tablets. They are also contraindicated in in pregnant or lactating women or women of premenopausal endocrine status.
Aromex Tablets – Dosage
The dosage of Aromex tablets is One 25 mg tablet once daily after a meal.
What to Do in Case You Miss a Dose of Generic Exemestane tablets
Take your missed dose of Generic Exemestane tablets as soon as you remember or, if it is nearly time for your next dose, skip your missed dose altogether. Do not double the next dose if you have missed one dose of Generic Exemestane tablets. Taking a double dose of Aromex will increase your risk of getting side effects.
Storage Instructions for Aromex Tablets
Store Aromex tablets at controlled room temperature 25°C (77°F). Excursions permitted to (59°F to 86°F, 15°C to 30°C). Protect from light.
During clinical trials Exemestane has been administered as a single dose to healthy female volunteers at doses as high as 800 mg and postmenopausal women with advanced breast cancer have been administered doses as high as 600 mg daily for 12 weeks. These dosages were well tolerated. There is no specific antidote to overdosage and treatment should be symptomatic. General supportive care, including frequent monitoring of vital signs and close observation of the patient, is recommended.
Warnings and Precautions to be taken when using Aromex Tablets
Before using Aromex tablets please inform your doctor about all the medicines that you take including no prescription medications, over the counter medicines and herbal remedies. Tell your doctor if you have a history or are suffering from any condition which affects the strength of your bones.
Aromex (Generic Exemestane tablets) may cause fetal harm when administered to a pregnant woman. Generic Exemestane should not be administered to premenopausal women. Aromex should not be coadministered with estrogen-containing agents as these medicines can interfere with its pharmacologic action.
Before treatment with Aromex, it is recommended that the patient's blood samples are checked to make sure that menopause is attained. Routine checking of your vitamin D level should also be made before treatment, and vitamin D supplement prescribed if levels are below normal. Hepatic Insufficiency:
Following a single 25-mg oral dose, the AUC of exemestane was approximately 3 times higher than that observed in healthy volunteers. The safety of chronic dosing in patients with moderate or severe hepatic impairment has not been studied. Renal Insufficiency:
The AUC of exemestane after a single 25-mg dose was approximately 3 times higher in subjects with moderate or severe renal insufficiency (creatinine clearance less than 35 mL/min/1.73 m2) compared with the AUC in healthy volunteers.The safety of chronic dosing in patients with moderate or severe renal impairment has not been studied.
Effects on Ability to Drive and Use Machines
Generic Exemestane is not likely to impair the ability of patients to drive and operate machinery. However, drowsiness, somnolence, asthenia and dizziness have been reported with the use of Aromex tablets.
Generic Exemestane should not be coadministered along with medicines containing oestrogen as these would negate its pharmacological action. No formal drug interaction studies have been conducted.
Generic Exemestane Side Effects
The most common Generic Exemestane side effects are hot flushes (22%), arthralgia (18%) and fatigue (16%). The other Aromex side effects are given below:
- Cardiovascular System: - chest pain or tightness sin chest, increased blood pressure, blood clots, heart attack, stroke.
- Central Nervous System: - headache, confusion, nausea, insomnia, mental depression, anxiety, dizziness.
- Eye and ENT: - problems with vision, speech, or balance, sore throat, runny nose.
- Gastrointestinal System: - constipation, indigestion, diarrhea, vomiting.
- Genitourinary System: - difficult, burning, or painful urination, frequent urge to urinate, vaginal bleeding, dark urine.
- Musculoskeletal System: - new or unusual bone pain, swelling of hands or feet, joint pain, lower back or side pain, osteoporosis.
- Respiratory System: - shortness of breath with mild exertion, cough.
- Hypersensitivity: - hives; difficult breathing; swelling of face, lips, tongue, or throat; fever; wheezing.
- General: - sudden numbness, weakness, hot flashes, increased appetite, loss of appetite, oedema of the extremities, increased sweating, general discomfort, hair loss, decreased sense of touch, burning, tingling, or prickly sensations, yellowing eyes/skin, carpal tunnel syndrome, weight gain.
Exemestane During Pregnancy
Exemestane has been classified by the US FDA as X. Exemestane can cause fetal harm when administered to a pregnant woman. Aromex is contraindicated in women who are or may become pregnant.If there is exposure to Exemestane during pregnancy, the patient must be informed of the potential hazard to the fetus and potential risk for loss of the pregnancy.
Aromex is contraindicated in pregnant women and only indicated in postmenopausal women. Exemestane and/or its metabolites appeared in rat milk within 15 minutes of oral administration of radiolabelled exemestane.
It is not known whether Exemestane is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised if a nursing woman is inadvertently exposed to Exemestane.
Do not use this medication if you are breast-feeding a baby.
Buy Generic Exemestane Tablets Online
You can buy Generic Exemestane 25 mg tablets online at a Cheap price from the Swiss Pharmacy. Generic Exemestane is available in pills of 25 mg . Aromex 25 mg pills are priced at only $1 per unit if you place an order for 270 tablets.
This Product was added to our catalogue on Wednesday, 20. July 2016.
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