Treatment of Gastrointestinal Infestations using Mebendazole Tablets

How is a Threadworm Infection Caused?

Threadworm is an intestinal infestation caused by Enterobius vermicularis which is acquired by swallowing the eggs. Threadworms look like tiny white threads and live in the bowel, attached to the lining. Usually the female worm starts producing the eggs two weeks after infestation. Normally the worms travel to the anus at night where they lay their eggs. The worms are often observed around the anal region early in the morning and sometimes cause itching. Restless sleep is a frequent sign of threadworms, especially in children. Scratching will cause threadworm eggs to stick to the fingers and reinfestation will result if the fingers are placed in the mouth. The eggs, which are too small to see, stick to whatever they come in contact with e.g. bedcloths, underwear, hands and food touched by contaminated hands. Threadworms are easily transmitted and even eggs floating in the air can be swallowed and cause infestation.

Treatment of Gastrointestinal Infestations Using Medications like Mebendazole Tablets (Generic Mebendazole)

Mebendazole Tablets (Generic Vermox or Lupimeb tablets) are used to treat worm infections of the gut such as pinworms as well as other other common worm infections such as whipworm, roundworm, hookworm, threadworm and tapeworm.
Mebendazole is a highly effective broad spectrum antihelmintic and works by selectively inhibiting the synthesis of microtubules in parasitic worms, and by destroying extant cytoplasmic microtubes in their intestinal cells: thereby blocking the uptake of glucose and other nutrients, resulting in the gradual immobilization and eventual death of the helminths. Mebendazole is only absorbed to a small extent.

Mebendazole Tablets – Active Ingredient

The active ingredient contained in Mebex Tablets is Mebendazole.

Mebendazole Tablets (Generic Mebendazole) – Availability and Packaging

Mebendazole Tablets are available as Lupimeb Tablets which are packaged in 100 mg tablets. They are manufactured by Lupin Limited, India. Mebendazole Tablets are also available as Vermox, Mebex, Ovex, Antiox, and Pripsen.

Mebendazole Tablets (Generic Mebendazole) – Dosage

The recommended dosage of Mebendazole Tablets (Generic Vermox) for various worm infections are given below:
Treatment of Threadworm Infestations:
The recommended dosage of Mebex tablets for adults as well as children above 2 years of age is 1 tablet (100 mg) given as a single dose. Since reinfections by Threadworm (Enterobius vermicularis) are known to be very common, it is recommended that the treatment be repeated after 2 and 4 weeks
Treatment of Hookworm, Whipworm and Roundworm Infestations:
The recommended dosage of Mebendazole tablets for adults as well as children above 2 years of age is a single dose of 1 tablet (100 mg) in the morning and evening for three consecutive days.

Mebendazole Tablets – Storage Requirements

Mebendazole Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Lupimeb Tablets (Generic Mebendazole) – Contraindications

Lupimeb tablets are contraindicated in individuals with a hypersensitivity to Mebendazole or any other inactive ingredient present in Generic Vermox. It is also contraindicated in pregnant women.

Side Effects Of Mebendazole Tablets (Lupimeb Tablets)

Mebendazole Tablets may cause some undesired side effects in a few patients, even though it is usually well tolerated at the recommended dose. The common side effects include transient abdominal pain, nausea, vomiting, headache, tinnitus, numbness, diarrhea, slight headache, fever, dizziness, exanthema, urticaria and angioedema.
Stop taking Lupimeb tablets and inform your doctor or health care provider immediately if you notice the following serious side effects: shortness of breath or wheezing, swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing, sudden or severe blisters, itching, skin rash, hives, flaking or peeling of skin.