Losacar Tablets (Generic Losartan) – Product Information
Losacar (Losartan) is indicated for the treatment of hypertension
Name of Drug
Manufacturer of Losacar Tablets (Generic Losartan)
Zydus Cadila website: zyduscadila.com
Active Pharmaceutical Ingredient
The active pharmaceutical ingredient contained in Losacar Tablets is Losartan.
Losacar (Generic Losartan)is indicated for the treatment of hypertension. It may be used alone or in combination with other agents. Losacar is also indicated to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy and for the treatment of diabetic nephropathy. It has less of an effect in black patients, similar to ACE inhibitors, such as captopril (Capoten), enalapril (Vasotec), and lisinopril (Zestril).
Losacar Tablets (Generic Losartan) – Dosage
Losartan may be given with or without food. Losartan is metabolized in the liver by cytochrome P450 enzymes to an active metabolite that is responsible for most of the drug activity. Reduction in dose by 50% is suggested in patients with impaired liver function. The Dosing of Losacar must be individualized. The usual starting adult dose of Losacar (Generic Losartan) is 50 mg once daily, with 25 mg being used as the starting dose in patients with possible depletion of intravascular volume for example patients treated with diuretics.
Drug Class and Mechanism
Losartan and its primary metabolite block the angiotensin receptor found in many tissues, primarily in vascular smooth muscle. Angiotensin, formed by the action of angiotensin converting enzyme (ACE), is a powerful chemical that causes blood vessel narrowing (vasoconstriction) which can lead to elevated blood pressure (hypertension).
Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.
Storage Instructions for Losacar Tablets
Tablets should be stored at room temperature in a tightly closed, light resistant container.
Warnings and Precautions to be taken when using Losacar Tablets
Use caution when driving, operating machinery, or performing other hazardous activities. Losartan may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Also use caution when rising from a sitting or lying position. Use alcohol cautiously. Alcohol may further lower blood pressure and increase drowsiness and dizziness while taking Losartan. Do not use salt substitutes or take potassium supplements without first talking to your doctor. Losartan can affect potassium levels in the body. When used in the second or third trimester of pregnancy, drugs that act by the same mechanism as Losartan can cause injury and even death to the fetus. Losartan should not be used during pregnancy. When pregnancy is detected, losartan should be stopped as soon as possible. Losartan is present in rat milk, and is toxic to rat neonates. Therefore, it should be avoided in nursing mothers.
Possible Side Effects of Losacar Tablets
In studies of over 4000 patients, including 1200 treated for over 6 months and 800 for over 1 year, the overall incidence of side effects was similar to placebo. Losacar Tablets (Losartan) is generally well tolerated. Side effects reported included diarrhea, muscle cramps, dizziness, insomnia, and nasal congestion.
More Information on Losacar Tablets
Stop taking Losacar Tablets (losartan) and contact your doctor immediately or seek emergency medical treatment If you experience any of the following serious side effects: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or little or no urine. Other side effects are less serious. Continue to take Losacar Tablets (losartan) and talk to your doctor if you experience diarrhea or upset stomach, muscle pain or cramps, dizziness, or insomnia. Side effects, other than those listed here, may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Buy Losacar Tablets 50 mg Online
You can buy Losacar Tablets (Generic Losartan) online from the Swiss Pharmacy. It is available in pills of 50 mg which are priced at only $0.84 per unit if you place an order for 180 tablets.
This Product was added to our catalogue on Saturday, 09. October 2010.